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When Picasso created “Still-Life with Chair Caning” in 1912, he flexed his artistic muscles by combining a variety of materials — paint, cloth, paper and rope — and produced what many consider the world’s first mixed media work of art. Mixed media is just that — art that utilizes more than one medium or material. Mixed media can incorporate paper, wood, fabric, metal and even random objects found by the artist or someone else. There really aren’t any restrictions. In the mixed media category at Sotheby’s Home, striking art combines various materials such as paint, paper, stone, metal and even buttons — often with a 3D effect — that will act as a remarkable addition to any room.